Granulomatous Tattoo reaction with Associated Uveitis successfully treated with methotrexate

by Science Editor
Medical Case Report

The medical literature contains a number patient case reports of inflammatory conditions and their temporal relationship with tattooing, in this particular case the reporting medical practitioners describe a case of Uveitis (inflammation of the middle layer of the eye wall the Uvea), these case reports provide important empirical evidence that is used by the medical profession to determine if certain types of chemicals in tattoo pigments pose a higher risk of triggering adverse health effects or if the individual cases are coincidental. Industry members should look upon these reports as contributing to the longer term safety of pigment manufacturing and client safety and by being aware of the types of health issues that are raising concerns by the treating doctors industry members are able to refer clients expeditiously if similar signs or symptoms after tattooing.

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Title: Granulomatous Tattoo reaction with Associated Uveitis successfully treated with methotrexate
Abstract: Case Report
A patient with no prior diagnosis of sarcoidosis who developed inflammation of tattooed skin and shortly after bilateral uveitis.
Industry Significance Rating: Medium - Industry wide monitoring is recommended.
Publication: Journal European Academy of Dermatology and Venereology. 08/02/2018.
Authors: Maijer KI, van der Bent SAS, Vercoutere W, Rustemeyer T.
Links:  Article Link Link to Publisher Search Google
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The authors describe an unusual case of uveitis with coexisting inflammatory reaction in a large number of black body art tattoos without diagnosis of sarcoidosis.

Some previous authors of cases involving uveitis and sarcoidosis associated with tattoos have also pondered if there is a causal relationship or if inflammatory reactions in tattoos might be considered a diagnostic marker, regardless of causation inflammatory reactions associated with tattoos warrant medical evaluation.


Clients who develop any form of skin reaction associated with a pre-existing or new tattoo should be referred to their treating doctor for evaluation.


Medical Report, body art tattoo, inflammation, granuloma, uveitis, black tattoo


The Education Team here at keeps a close eye on the scientific and medical literature for new publications relating to cosmetic and medical tattooing that may be of interest to our customers. The intent is to alert industry members to important publications within the literature to expand the knowledge base particularly in relation to high impact reports.

NB. does not host this publication on our server we merely provide an overview with links to the publisher, the authors and their publisher hold copyright to the actual article.


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