Papulo-Nodular Reactions in Black Tattoos as Markers of Sarcoidosis

by Science Editor

This systematic study aims to find out if sarcoidosis is more prevalent in those with black tattoos.

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Papulo-Nodular Reactions in Black Tattoos as Markers of Sarcoidosis: Study of 92 Tattoo Reactions from a Hospital Material.
Section title: Tattoo and Body Art - Original Paper.

Abstract: Sarcoidosis is, from historical data, suggested to be more prevalent among patients with tattoo reactions. We aimed to evaluate this association in a systematic study.
Industry Significance Rating:

High - Industry alert, report has major implications related to health and safety.


Dermatology. 2017 Feb 7. doi: 10.1159/000453315. [Epub ahead of print].

Authors: Sepehri M, Hutton Carlsen K, Serup J.
Links:  Article Link Link to Publisher Search Google
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The authors noted that based upon historical data Sarcoidosis appears to be more prevalent among patients with tattoo reactions and they evaluated the potential association in their systematic study.

In their conclusion the authors noted that "black tattoos with papulo-nodular reactions should be seen as markers of sarcoidosis" and that depending on individual predisposition "Papulo-nodular reactions may, as triggers, induce widespread reactions in other black tattoos" describing this as a “rush phenomenon” .

The authors estimated that Sarcoidosis to have a 500-fold increased in papulo-nodular reactions as compared to the prevalence in the general population, and they considered that association with black tattoos is "strong"


Suggest that clients with body art who exhibit papulo-nodular reactions within black tattoos (e.g. granuloma's) are referred to their treating doctor for evaluation particularly if more than one tattoo is involve.


Scientific Report,  body art tattoo, systemic sarcoidosis, black tattoo, papulo-nodular, adverse reactions, rush phenomenon


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